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Updated: Apr 5, 2026

Improved Home Blood Pressure Control by CT-guided Ozone-mediated Renal Denervation for Patients with Resistant Hypertension
Published on: June 6, 2025
[THE TREATMENT OF HIGH BLOOD PRESSURE MUST BE TAILOR-MADE]
Insights
Hypertension affects over 25% globally, posing a significant cardiovascular risk. Personalized treatment, guided by physician experience, is key to optimizing blood pressure control when guidelines fall short.
Area of Science:
- Cardiology
- Public Health
Background:
- Hypertension is a widespread global health issue, impacting over 25% of the population and recognized as a leading cause of cardiovascular disease.
- Despite existing international guidelines, optimal blood pressure control remains a challenge, highlighting the need for improved management strategies.
Purpose of the Study:
- To explore personalized approaches for hypertension management.
- To evaluate the current role of emerging tools like pharmacogenetics and pharmacometabolomics.
- To emphasize the importance of physician experience and patient education in optimizing hypertension treatment.
Main Methods:
- Review of current hypertension prevalence and management challenges.
- Discussion of advanced diagnostic tools (pharmacogenetics, pharmacometabolomics).
- Emphasis on clinical judgment and patient-centered strategies.
Main Results:
- Personalized hypertension management offers a promising avenue for improving patient outcomes.
- While novel tools are developing, their clinical application is not yet established.
- Physician experience remains the most reliable factor in tailoring treatment plans.
- Patient education is vital for enhancing medication adherence and treatment success.
Conclusions:
- Optimizing hypertension control requires a personalized approach, integrating physician expertise with patient-specific factors.
- Further research and validation are needed for advanced tools before widespread clinical adoption.
- Effective patient education is fundamental to successful long-term hypertension management.
Abstract:
Hypertension has a high world-wide prevalence, affecting more than 25 % of the population; it remains the silent killer number one in cardiovascular pathology. Although lowering high blood pressure is protective, perfect control of hypertension is far from being optimal in spite of many international guidelines regularly updated according to published scientific studies. A personalized approach of hypertension management is an attractive way to improve this situation. Tools are developing (pharmacogenetics, pharmacometabolomics), but their use in daily clinical practice seems premature. At the present time, it is the physician experience which offers the best opportunity to propose the best treatment to the best patient. The management of hypertension remains a difficult task in some cases. Patient education is also crucial to improve drug compliance.
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