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Inhibition of Topoisomerase (DNA) I (TOP1): DNA Damage Repair and Anticancer Therapy

Yang Xu1, Chengtao Her2

  • 1School of Molecular Biosciences, College of Veterinary Medicine, Washington State University, Mail Drop 64-7520, Pullman, WA 99164, USA. davidxy22@vetmed.wsu.edu.

Biomolecules
|August 20, 2015
PubMed

Keywords:
DNA double-strand break (DSB)DNA replicationDSB repairanticancer therapyhomologous recombination (HR)non-homologous end joiningone-ended DSBsingle-strand break (SSB) repairtopoisomerase (DNA) I (TOP1)topoisomerase inhibitor

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