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Calciphylaxis with evidence of hypercoagulability successfully treated with unfractionated heparin: a

A Carter1, A G Ortega-Loayza2, J Barrett3

  • 1Department of Dermatology, New York Medical College, New York, NY, USA.

Clinical and Experimental Dermatology
|August 21, 2015
PubMed

Insights

Calciphylaxis, a condition causing abnormal blood vessel and skin calcification, has unclear causes. This case highlights that treating calciphylaxis may benefit from exploring hypercoagulable states and considering anticoagulation therapy.

Area of Science:

  • Vascular Biology
  • Dermatology
  • Nephrology

Background:

  • Calciphylaxis involves abnormal calcification of blood vessels and skin, with unclear etiology and pathogenesis.
  • Frequently associated conditions include end-stage renal disease, diabetes mellitus, and hyperparathyroidism.
  • Skin lesions can be sudden, rapidly progressing, and are most common on the legs.

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