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A screening method using tissue culture for evaluation of potential retinal adhesives
M J Jaffe1, A P Oliver, M A Von Fricken
1Neuropsychiatry Branch, National Institute of Mental Health, Washington, DC.
Retina (Philadelphia, Pa.)
|January 1, 1989
Abstract:
Several adhesives have been tested for their potentially toxic effects on embryonic retinal tissue. The authors have characterized the effects of the adhesives on neurofilament extension and also on surgical-wound "re-knitting." While none of the adhesives in the sample (including those in current surgical use) seem to be ideal, the model advanced has application for the continuing development of better 'bio-adhesives'. The most immediate application is within the field of vitreoretinal surgery in situations where conventional procedures currently seem inadequate.