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Updated: Apr 5, 2026

A Rat Model of Mild Intrauterine Hypoperfusion with Microcoil Stenosis
Published on: January 7, 2018
Umbilical Cord Coiling and Zygosity: Is there a Link?
André Joannou Coetzee1, Eumenia Castro2, Luiz Cesar Peres1
1a Department of Histopathology , Sheffield Children's Hospital , Western Bank , United Kingdom.
Introduction:
The aim of this study was to analyze abnormalities of umbilical coiling index (UCI) in twin gestation to test whether the coiling is genetically influenced by zygosity.
Methods:
Data retrieved comprised gestational age (GA), chorionicity, fetal gender, and UCI.
Results:
The mean UCI of hypercoiled cords in monochorionic placentas was 0.55 coils/cm and 0.49 coils/cm in dichorionic placentas with discordant fetal gender (P = 0.2629).
Discussion:
In conclusion, no significant statistical difference between UCI in monochorionic and dichorionic twin placentas with discordant fetal gender was identified, suggesting that zygosity does not play a role in umbilical coiling induction.
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