[Features of nutrition and biosynthesis of protein in animals of various ages]

Age-dependent features of protein synthesis intensity were studied in tissues (liver, muscles, plasma) by the method of continuous constant L-(1-14C)-leucin infusion. The investigation was conducted in male rats aged 4 and 24 months that were bred in large and small holes, and received rations with varying protein content (2.5, 15 and 60% of casein). It has been shown that protein synthesis intensity in the tissues studied is not lowered with age, in the liver it is higher than in the muscles. Differences in the early postnatal nutrition (breeding of the animals in large and small holes) has not influenced protein synthesis in the tissues. A tendency has been observed to activation of protein synthesis in the liver with lowering protein level in the diet.