[The effect of oral administration of glycine on metabolism]

Dietary supplied glycine resulted in dose-dependent effects on the growth of experimental animals, on diet-induced thermogenesis and on food efficiency. Furthermore it is possible to influence activities of enzymes involved in glycine metabolism and other enzyme activities in liver tissue by increased glycine supply. Simultaneously, changes occurred in amino acid levels in blood, tissues and urine, in the extent of urea excretion and in glycine metabolism. Based on these results no satisfactory explanation can be given concerning the possible biochemical mechanisms of the glycine-induced reduction in food efficiency at present.