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Updated: Apr 5, 2026

Synthesis of Core-shell Lanthanide-doped Upconversion Nanocrystals for Cellular Applications

Synthesis of Core-shell Lanthanide-doped Upconversion Nanocrystals for Cellular Applications

Published on: November 10, 2017

Multimodal cancer imaging using lanthanide-based upconversion nanoparticles.

Dongmei Yang¹, Chunxia Li¹, Jun Lin¹

¹State Key Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130024, P. R. China.

Nanomedicine (London, England)

|August 22, 2015

Summary

This summary is machine-generated.

Lanthanide-based upconversion nanoparticles (UCNPs) offer synergistic multimodal imaging for enhanced cancer diagnosis and research. This review highlights UCNP optimizations, applications, and future perspectives in nanomedicine.

Keywords:

MRI diagnosis drug delivery lanthanides multimodal imaging nanoparticles targeting therapy upconversion upconversion luminescence imaging x-ray computed tomography imaging

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Area of Science:

Nanotechnology and Materials Science
Biomedical Imaging
Cancer Research

Background:

Multimodal nanoprobes integrate diverse imaging techniques for improved diagnostic efficiency and accuracy.
Lanthanide-based upconversion nanoparticles (UCNPs) possess unique properties making them ideal for developing advanced multimodal bioprobes.

Purpose of the Study:

To review recent advancements in optimizing existing UCNPs.
To highlight the applications of lanthanide-based UCNPs in multimodal cancer imaging (in vitro and in vivo).
To discuss UCNP-based nanoprobes for targeted diagnosis and image-guided therapeutics.

Main Methods:

Literature review of recent research on UCNP optimization and applications.
Focus on lanthanide-based UCNPs for multimodal cancer imaging.
Exploration of UCNPs in targeted diagnosis and theranostics.

Main Results:

Optimizations of UCNPs enhance their performance for biomedical applications.
Lanthanide-based UCNPs demonstrate significant potential in multimodal cancer imaging.
UCNP-based nanoprobes are being explored for targeted diagnosis and image-guided therapy.

Conclusions:

Lanthanide-based UCNPs are versatile platforms for multimodal nanoprobes.
These nanoprobes show promise for advancing cancer diagnosis and treatment.
Further research is needed to address challenges and realize the full potential of UCNPs in nanomedicine.