Is the Pulmonary Embolism Severity Index Being Routinely Used in Clinical Practice?

Ali Shafiq1, Hamza Lodhi2, Zaheer Ahmed1

  • 1Saint Luke's Mid America Heart Institute, 4401 Wornall Road, Kansas City, MO 64111, USA ; University of Missouri-Kansas City, 2411 Holmes Street, Kansas City, MO 64108, USA.

Thrombosis
|August 22, 2015
PubMed

Insights

The Pulmonary Embolism Severity Index (PESI) score did not significantly differentiate hospital stays for pulmonary embolism (PE) patients. Few low-risk PE patients were discharged early, questioning the widespread clinical utility of PESI.

Area of Science:

  • Pulmonary Medicine
  • Cardiology
  • Critical Care Medicine

Background:

  • The Pulmonary Embolism Severity Index (PESI) is a tool for risk stratification in pulmonary embolism (PE) patients.
  • The widespread clinical utility and impact of the PESI score on patient management remain uncertain.
  • This study investigates the effectiveness of PESI in guiding hospital stay duration and early discharge for PE patients.

Purpose of the Study:

  • To compare the length of hospital stay among low, moderate, and high-risk PE patients as stratified by the PESI score.
  • To determine the proportion of low-risk PE patients who are discharged early (within 3 days).
  • To assess the practical application and widespread use of the PESI score in clinical settings.

Main Methods:

  • A retrospective review of 315 pulmonary embolism patients admitted to St. Joseph Mercy Oakland Hospital from January 2005 to August 2010.
  • Patients were stratified into low (<85), moderate (86-105), and high (>105) risk categories using the PESI score.
  • Comparison of length of hospital stay across risk groups and calculation of early discharge rates for low-risk patients.

Main Results:

  • Over half (51.7%) of the 315 PE patients were classified as low risk.
  • No statistically significant difference was observed in the length of hospital stay between low-risk (7.11 ± 3 days) and moderate-risk (6.88 ± 2.9 days) groups (p > 0.05).
  • Similarly, no significant difference in hospital stay was found between low-risk and high-risk (7.28 ± 3.0 days) groups (p > 0.05), with only 9% of low-risk patients discharged within 3 days.

Conclusions:

  • The PESI score did not demonstrate a significant difference in hospital length of stay between low and high-risk PE patient groups.
  • A small proportion of low-risk PE patients were discharged early, suggesting limited impact of the PESI score on early discharge decisions.
  • These findings raise questions about the widespread clinical applicability and utility of the PESI score for managing PE patients and optimizing hospital resource utilization.

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