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[Different methods of determining the position on the oxyhemoglobin dissociation curve]
P50 values, as measured on DCA-1 analyzer and calculated according to Lichtman formula based on Hill equation, or calculated according to standard Severinghaus curve have been compared. No significant differences in P50 values have been observed. The method of direct oxyhemoglobin dissociation curve registration seems preferable, as it gives the idea not only of the position, but also of the form of curve changes. However, it cannot be widely recommended for clinical practice for lack of home-made equipment. Calculation methods are simpler, however, they depend on the accuracy of SO2 measurements and the necessity to use for calculations the results of blood pO2 measurements with SO2 in the range of 25-75%.
P50 values, as measured on DCA-1 analyzer and calculated according to Lichtman formula based on Hill equation, or calculated according to standard Severinghaus curve have been compared. No significant differences in P50 values have been observed. The method of direct oxyhemoglobin dissociation curve registration seems preferable, as it gives the idea not only of the position, but also of the form of curve changes. However, it cannot be widely recommended for clinical practice for lack of home-made equipment. Calculation methods are simpler, however, they depend on the accuracy of SO2 measurements and the necessity to use for calculations the results of blood pO2 measurements with SO2 in the range of 25-75%.