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Best Practices in Alemtuzumab Administration: Practical Recommendations for Infusion in Patients With Multiple
Lynn McEwan1, Christina Caon, Carol Chieffe
1London Health Sciences Centre, London, Ontario, Canada (Ms McEwan); Multiple Sclerosis Center, Wayne State University School of Medicine, Detroit, Michigan (Ms Caon); Neuroscience Center, Allegheny General Hospital, Pittsburgh, Pennsylvania (Ms Chieffe); Central Texas Neurology Consultants, Round Rock, Texas (Dr Mayer); Multiple Sclerosis Comprehensive Care Center, Baylor College of Medicine, Houston, Texas (Ms Saldana-King); Genzyme, Cambridge, Massachusetts (Dr Miller). Lynn McEwan, MScN, NP, MSCN, CNNc, is a nurse practitioner at the Multiple Sclerosis Clinic of the London Health Sciences Centre in London, Ontario, Canada. She has specialized in the care of patients with multiple sclerosis for 25 years and is certified in multiple sclerosis and neuroscience nursing. Ms. McEwan has published and lectured on a variety of multiple sclerosis-related topics from disease management to nursing. She is a past president of the Multiple Sclerosis Nursing International Certification Board. Christina Caon, MSN, RN, NP-C, is a nurse practitioner and the assistant director of clinical research at the Multiple Sclerosis Center at Wayne State University. She has been involved with clinical trial research and numerous investigator-initiated trials for more than 14 years. She also has been an invited speaker and presented data at numerous national and international meetings focused on multiple sclerosis. Carol Chieffe, MSCN, RN, CCRC, is a clinical nurse at Allegheny General Hospital's Multiple Sclerosis Treatment Center, where she was instrumental in the development of the infusion center. She is active with the National Multiple Sclerosis Society as a health care advocate for government affairs on the state and federal levels. Lori Mayer, DNP, MSN, RN, the director of medical research services for the Multiple Sclerosis Clinic of Central Texas, manages multiple sclerosis clinical research programs, patient-centered education, and clinical care. In addition, she writes posters an
Nursing experts developed best-practice recommendations for alemtuzumab infusions in multiple sclerosis (MS) patients. This guide helps optimize patient education and manage infusion reactions for better MS care.
Area of Science:
- Neurology
- Nursing Science
Background:
- Multiple sclerosis (MS) care is increasingly complex, placing greater responsibility on nursing professionals.
- Nurses are crucial in educating patients on disease-modifying therapies (DMTs), treatment courses, and managing adverse effects.
Purpose of the Study:
- To establish best-practice recommendations for administering alemtuzumab infusions in MS patients.
- To provide a practical guide for clinicians to enhance patient education and manage infusion-associated reactions.
Main Methods:
- A panel of nursing and multiple sclerosis experts was convened.
- A modified Delphi method was employed to reach consensus on recommendations.
Main Results:
- Consensus was reached on best-practice recommendations for alemtuzumab infusion.
- The recommendations focus on optimizing patient education and managing infusion-associated reactions.
Conclusions:
- This resource offers practical guidance for clinicians administering alemtuzumab.
- Implementing these recommendations can improve patient education and safety during alemtuzumab infusions for MS.
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