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Activity of Posterior Lateral Line Afferent Neurons during Swimming in Zebrafish

Activity of Posterior Lateral Line Afferent Neurons during Swimming in Zebrafish

Published on: February 10, 2021

The pescatorial sixth.

Francesco Pellegrini¹, Giovanni Prosdocimo², Jason J S Barton³

¹Neuro-Ophthalmology Service, Department of Ophthalmology, Conegliano Hospital, Conegliano, Treviso, Italy.

Survey of Ophthalmology

|August 23, 2015

Summary

This summary is machine-generated.

Miller-Fisher syndrome, a rare autoimmune disorder, can present with ophthalmoplegia (paralysis of eye muscles) and ataxia (loss of coordination). This case highlights a variant without ataxia, emphasizing the need for prompt diagnosis in patients with bilateral VI nerve palsies.

Keywords:

Miller-Fisher syndrome areflexia diplopia ophthalmoplegia sixth nerve palsy

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Area of Science:

Neurology
Autoimmune Diseases
Ophthalmology

Background:

Miller-Fisher syndrome (MFS) is a rare variant of Guillain-Barré syndrome, characterized by ophthalmoplegia, ataxia, and areflexia.
The classic MFS triad is often preceded by infectious triggers, such as gastroenteritis.

Observation:

A 56-year-old male with diabetes presented with acute diplopia and bilateral complete abduction deficits.
Initial examination revealed diffuse areflexia; however, the patient subsequently developed complete ophthalmoplegia and ataxia.
A history of possible gastroenteritis 3 weeks prior to symptom onset was elicited.

Findings:

The clinical presentation was consistent with Miller-Fisher syndrome.
This case illustrates an atypical "ophthalmoplegia without ataxia" variant of MFS.
Bilateral VI nerve palsies were a key presenting feature.

Implications:

The "ophthalmoplegia without ataxia" variant of MFS should be considered in the differential diagnosis of patients presenting with bilateral VI nerve palsies.
Early recognition and diagnosis of MFS variants are crucial for timely management and improved patient outcomes.
Understanding atypical presentations of MFS aids in refining diagnostic criteria and treatment strategies for autoimmune neuropathies.