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Resveratrol and anti-atherogenic effects
Graziano Riccioni1, Maria Alessandra Gammone2, Guido Tettamanti3
1a Cardiology Unit, San Camillo de Lellis Hospital , Manfredonia , Foggia , Italy .
International Journal of Food Sciences and Nutrition
|August 27, 2015
Summary
Resveratrol, found in red wine and the Mediterranean diet, combats atherosclerosis by reducing inflammation and oxidative stress. This natural compound is safe and effective in preventing cardiovascular disease.
Area of Science:
- Cardiovascular Science
- Nutritional Biochemistry
Background:
- Inflammation and oxidative stress are key drivers in atherosclerosis development, influencing all disease stages.
- Resveratrol, a polyphenol in grapes and red wine, is recognized for its therapeutic potential.
- Epidemiological studies link the resveratrol-rich Mediterranean diet to lower atherosclerosis risk.
Purpose of the Study:
- To review the anti-atherogenic properties of resveratrol.
- To highlight resveratrol's role in mitigating inflammation and oxidative stress.
Main Methods:
- Review of epidemiological studies and molecular research on resveratrol.
- Analysis of resveratrol's effects on lipid metabolism, oxidative stress markers, and platelet function.
Main Results:
- Resveratrol decreases low-density lipoprotein cholesterol and reduces lipid peroxidation.
- It inhibits platelet aggregation and combats oxidative stress.
- Resveratrol demonstrates a broad range of molecular targets and functions.
Conclusions:
- Resveratrol is a safe and effective anti-atherogenic agent.
- Its properties support the cardiovascular benefits observed with the Mediterranean diet.
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