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[A case of adenomatoid mesothelioma of the pleura]
Abstract:
A case of adenomatoid mesothelioma of the pleura was presented. The patient was a 69-year-old woman with diabetes mellitus. She was admitted to our hospital because of a chest roentgenographic abnormality, which was pointed out during her clinical course. Chest X-ray-film on admission revealed a semicircular lesion located in the left lower lung field. The physical examination and laboratory data showed no abnormalities. Left lower lobectomy was performed. The tumor was approximately, 3.0 x 3.0 x 3.0 cm, elastic soft, encapsulated, and originated from the pulmonary pleura. The histological findings of the tumor showed benign epithelial localized pleural mesothelioma. However histologically, the tumor tissue was not like the usual epithelial type. That is, most cells which had intracellular vacuoles, were similar to signet ring cell. The tumor was diagnosed as adenomatoid mesothelioma of the pleura.
Insights
This case report details an adenomatoid mesothelioma of the pleura, a rare benign pleural tumor. Diagnosis was confirmed through histological examination of a resected tumor.
Area of Science:
- Thoracic Surgery
- Pathology
- Oncology
Background:
- Pleural mesothelioma represents a rare group of neoplasms arising from the mesothelial cells lining the pleural cavity.
- Adenomatoid mesothelioma is a rare, benign variant typically presenting as a localized pleural tumor.
Observation:
- A 69-year-old female patient with diabetes mellitus presented with a chest roentgenographic abnormality.
- Imaging revealed a semicircular lesion in the left lower lung field; physical and laboratory data were unremarkable.
- Surgical resection (left lower lobectomy) was performed for the approximately 3.0 x 3.0 x 3.0 cm tumor originating from the pulmonary pleura.
Findings:
- Histological examination revealed a benign epithelial localized pleural mesothelioma.
- Unusually, the tumor cells exhibited intracellular vacuoles, resembling signet ring cells, distinguishing it from typical epithelial mesothelioma.
- The final diagnosis was adenomatoid mesothelioma of the pleura.
Implications:
- This case highlights the importance of considering rare histological variants in the differential diagnosis of pleural tumors.
- Recognizing the unique cellular morphology of adenomatoid mesothelioma is crucial for accurate diagnosis and appropriate patient management.
- Further studies may elucidate the specific cellular pathways and clinical behavior of this uncommon pleural neoplasm.