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Updated: Apr 4, 2026

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Type 2 segmental glomangioma--Case report.

Camila Raposo Cabral1, Jayme de Oliveira Filho1, Julliene Lika Matsumoto1

  • 1Universidade de Santo Amaro, Santo Amaro, SP, BR.

Anais Brasileiros De Dermatologia
|August 28, 2015
PubMed
Summary

Multiple glomangiomas, rare vascular tumors, can present from birth and spread throughout the body. Histopathological diagnosis is crucial for differentiating these asymptomatic childhood lesions from other vascular malformations.

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Area of Science:

  • Vascular Tumors
  • Dermatology
  • Genetics

Background:

  • Glomus tumors are neoplasms derived from modified perivascular cells.
  • Multiple glomangiomas, often asymptomatic and more common in childhood, can be inherited in an autosomal dominant pattern.
  • These lesions can be misdiagnosed as other vascular malformations.

Observation:

  • A case report details a patient with congenital hemangiomatous lesions on the calcaneus and wrist.
  • Lesions progressively disseminated throughout the body over a 6-year period.
  • The patient presented with type 2 segmental glomangiomatosis.

Findings:

  • The segmental manifestation is hypothesized to result from genetic mutation and loss of heterozygosity.
  • Dissemination of lesions with growth is attributed to mutations in distant skin areas.
  • Histopathological examination is essential for accurate diagnosis.

Implications:

  • This case highlights the importance of considering multiple glomangiomas in the differential diagnosis of childhood vascular lesions.
  • Understanding the genetic basis, such as loss of heterozygosity, aids in explaining lesion dissemination.
  • Conservative management is typically recommended for asymptomatic multiple glomangiomas.