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Chronic bacterial prostatitis and chronic pelvic pain syndrome
Diana K Bowen1, Elodi Dielubanza, Anthony J Schaeffer
1Department of Urology, Northwestern University, Feinberg School of Medicine, Chicago, US.
BMJ Clinical Evidence
|August 28, 2015
Summary
This overview examines treatments for chronic prostatitis, including chronic bacterial prostatitis and chronic pelvic pain syndrome. It categorizes the efficacy of 12 interventions for these conditions.
Area of Science:
- Urology
- Evidence-Based Medicine
Background:
- Chronic prostatitis presents as chronic bacterial prostatitis (CBP) with infection, or chronic pelvic pain syndrome (CPPS) without infection.
- CBP often involves recurrent urinary tract infections, while CPPS etiology and natural history remain unclear.
Purpose of the Study:
- To systematically review the effects of various treatments for chronic bacterial prostatitis.
- To systematically review the effects of various treatments for chronic pelvic pain syndrome.
Main Methods:
- A systematic overview was conducted, searching major databases up to February 2014.
- Included studies were screened, appraised, and 16 full publications were evaluated, resulting in the inclusion of three systematic reviews and one RCT.
- GRADE evaluation was performed for 14 PICO combinations.
Main Results:
- The overview identified and evaluated 12 distinct interventions for prostatitis.
- Data on the effectiveness and safety of these interventions were compiled.
Conclusions:
- The efficacy of 12 interventions for chronic prostatitis was categorized.
- Interventions assessed include 5 alpha-reductase inhibitors, allopurinol, alpha-blockers, antimicrobial drugs (oral and injected), mepartricin, NSAIDs, pentosan polysulfate, quercetin, sitz baths, TUMT, and TURP.
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