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Electronic Tongue Generating Continuous Recognition Patterns for Protein Analysis
Published on: September 16, 2014
An optical nanoruler based on a conjugated polymer-silver nanoprism pair for label-free protein detection
Xiaoyu Wang1,2, Shengliang Li2, Pengbo Zhang2
1State Key Laboratory for Advanced Metals and Materials, School of Materials Science and Engineering, University of Science and Technology Beijing, Beijing, 100083, P. R. China.
Abstract:
An optical nanoruler system based on a conjugated polyelectrolyte-silver nanoprism pair is developed for label-free protein detection by taking advantage of the metal-enhanced fluorescence effect of silver nanostructures. Antibody-antigen interactions induce a change in the metal-fluorophore distance, followed by the response of a fluorescent signal of the conjugated polyelectrolyte. The system is used to detect target antigens sensitively and selectively.
