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Updated: Apr 4, 2026

Cell Squeezing as a Robust, Microfluidic Intracellular Delivery Platform
Published on: November 7, 2013
Nano-enabled delivery of diverse payloads across complex biological barriers
Kathleen A Ross1, Timothy M Brenza1, Andrea M Binnebose2
1Chemical and Biological Engineering, Iowa State University, 2114 Sweeney Hall, Ames 50011, USA.
Abstract:
Complex biological barriers are major obstacles for preventing and treating disease. Nanocarriers are designed to overcome such obstacles by enhancing drug delivery through physiochemical barriers and improving therapeutic indices. This review critically examines both biological barriers and nanocarrier payloads for a variety of drug delivery applications. A spectrum of nanocarriers is discussed that have been successfully developed for improving tissue penetration for preventing or treating a range of infectious, inflammatory, and degenerative diseases.
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