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A study on the recent trend and risk factors of cerebrovascular disease
Insights
Cerebral infarction incidence increased, with higher lipid levels and hematocrit compared to cerebral hemorrhage. Hypertension was the most common preceding condition for cerebrovascular disease.
Area of Science:
- Neurology
- Cardiovascular Medicine
- Epidemiology
Background:
- Cerebrovascular diseases pose a significant health burden.
- Understanding risk factors and differences between subtypes is crucial for effective management.
Purpose of the Study:
- To analyze the incidence and clinical characteristics of cerebrovascular diseases.
- To compare cerebral infarction and cerebral hemorrhage based on patient demographics and biochemical markers.
Main Methods:
- Retrospective analysis of 687 cerebrovascular disease cases confirmed by CT scan.
- Evaluation of patient data including age, preceding diseases, and lipid profiles.
Main Results:
- Cerebral infarction incidence showed a marked increase.
- Hypertension was the most frequent preceding condition.
- Cerebral infarction patients had higher total lipid, total-cholesterol/HDL-cholesterol ratio, triglyceride, and total cholesterol levels, with significantly lower HDL-cholesterol.
- Higher hematocrit and hemoglobin levels were observed in cerebral infarction.
Conclusions:
- Cerebral infarction and cerebral hemorrhage exhibit distinct epidemiological and biochemical profiles.
- Hypertension is a key risk factor for cerebrovascular disease.
- Further research into lipid metabolism and hematological factors in cerebrovascular disease is warranted.
Abstract:
Six hundred eighty seven cases of cerebrovascular disease, confirmed by C-T scan, were evaluated at Hanyang University Hospital from January 1985, to December 1988, and the following results were obtained. 1) The incidence of cerebral infarction was markedly increased in the last 5 years. 2) Cerebral hemorrhage showed a peak age of incidence in the fifties, cerebral infarction in the sixties. 3) Among the preceding diseases at the onset of cerebrovascular disease, hypertension was the most common. 4) Total lipid, Total-cholesterol/HDL-cholesterol ratio were significantly higher in cerebral infarction than in cerebral hemorrhage. 5) Triglyceride concentration and total cholesterol concentration were also higher in cerebral infarction than those of cerebral hemorrhage, but statistically not significant. 6) In cerebral infarction HDL-cholesterol concentration was significantly lower than that of cerebral hemorrhage. (p less than 0.01.) 7) In cerebral infarction, hematocrit and hemoglobin concentration were significantly higher, respectively, than those of cerebral hemorrhage.