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Recurrent Escherichia coli Urinary Tract Infection Triggered by Gardnerella vaginalis Bladder Exposure in Mice
Published on: December 4, 2020
[To treat or not to treat asymptomatic bacteriuria before methylprednisolone perfusion]
C Donzé1, A Dinh2, O Heinzlef3
1Service de médecine physique et réadaptation fonctionnelle, groupement hospitalier de l'institut catholique de Lille, rue du Grand-But, BP 249, 59462 Lomme cedex, France.
Abstract:
The prescription of methylprednisolone for multiple sclerosis acute relapse involves sterilization of urine. An observational study was conducted to clarify the benefit of antibiotic prophylaxis in case of asymptomatic bacteriuria found before methylprednisolone. Ninety-seven patients were included; 32 patients had asymptomatic bacteriuria. Seventeen patients were treated and 15 were not. The number of urinary tract infections in the month following the methylprednisolone was the same in the two groups. The results seem in favor of a therapeutic abstention. A larger study will be performed to confirm these results and determine appropriate recommendations.
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