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Gender difference in outcome after total knee replacement.

Jason Beng Teck Lim1, Chong Hwei Chi, Lup Ean Lo

  • 1Department of Orthopaedic Surgery, Singapore General Hospital, Singapore.

Journal of Orthopaedic Surgery (Hong Kong)
|September 1, 2015
PubMed
Summary
This summary is machine-generated.

Women with knee osteoarthritis (OA) showed poorer preoperative function but achieved greater improvements after total knee replacement (TKR) compared to men. This study highlights sex-based differences in TKR outcomes for knee OA.

Keywords:
arthroplasty, replacement, kneesextreatment outcome

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Area of Science:

  • Orthopedic Surgery
  • Biomedical Engineering
  • Rehabilitation Science

Background:

  • End-stage knee osteoarthritis (OA) significantly impacts quality of life.
  • Total knee replacement (TKR) is a common surgical intervention for knee OA.
  • Understanding sex-based differences in TKR outcomes is crucial for personalized patient care.

Purpose of the Study:

  • To compare outcomes between men and women undergoing primary total knee replacement (TKR) for end-stage knee osteoarthritis (OA).
  • To analyze differences in preoperative function and postoperative recovery between sexes.

Main Methods:

  • Retrospective review of 214 men and 1040 women undergoing primary TKR for knee OA.
  • Minimum 2-year follow-up period.
  • Assessment of knee flexion, Oxford Knee Score, Knee Society Score (KSS), and SF-36 subscores preoperatively and postoperatively.

Main Results:

  • Men had lower BMI and better preoperative knee flexion, Oxford Knee Score, KSS, and SF-36 scores compared to women.
  • Women demonstrated significantly greater improvement in Oxford Knee Score and KSS knee score at 6 months and 2 years post-TKR.
  • Women also showed greater improvement in SF-36 social functioning and mental health subscores at 2 years.

Conclusions:

  • Despite poorer preoperative status, women experience greater functional gains after TKR for knee OA.
  • Sex-based differences in recovery trajectories warrant consideration in patient counseling and rehabilitation strategies.
  • TKR offers substantial, and in some aspects greater, improvement for women with knee OA compared to men.