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Related Concept Videos

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A population is composed of members of the same species that simultaneously live and interact in the same area. When individuals in a population breed, they pass down their genes to their offspring. Many of these genes are polymorphic, meaning that they occur in multiple variants. Such variations of a gene are referred to as alleles. The collective set of all the alleles within a population is known as the gene pool.
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Following the Dynamics of Structural Variants in Experimentally Evolved Populations
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Paramutation in evolution, population genetics and breeding.

Nathan M Springer1, Karen M McGinnis2

  • 1Microbial and Plant Genomics Institute, Department of Plant Biology, University of Minnesota, Saint Paul, MN 55108, USA.

Seminars in Cell & Developmental Biology
|September 2, 2015
PubMed
Summary
This summary is machine-generated.

Paramutation, an epigenetic process causing heritable allele changes, is not well understood in terms of its prevalence or genetic basis. Further research is needed to explore its role in plant evolution and breeding.

Keywords:
EvolutionParamutationPopulation genetics

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Area of Science:

  • Genetics
  • Epigenetics
  • Plant Biology

Background:

  • Paramutation involves directed allelic interactions causing heritable changes in allele states.
  • While characterized at some loci, the genome-wide prevalence of paramutable/paramutagenic alleles remains largely unknown.
  • Understanding paramutation is crucial for evolutionary studies and crop improvement.

Purpose of the Study:

  • To investigate the genetic and epigenetic factors underlying paramutation.
  • To determine the prevalence of paramutation across genomes and populations.
  • To explore the inheritance patterns of paramutation events in various breeding and natural contexts.

Main Methods:

  • Analysis of epigenetic regulation and genetic sequences involved in paramutation.
  • Surveys of allele prevalence and paramutation frequency in populations.
  • Modeling of inheritance factors such as epigenetic stability, mating systems, and ploidy.

Main Results:

  • Paramutation involves specific genetic sequences interacting with epigenetic regulatory mechanisms.
  • Evidence suggests paramutation-like chromatin and expression changes occur at numerous loci.
  • Inheritance is influenced by epigenetic state stability, mating behavior, and ploidy levels.

Conclusions:

  • Clarifying paramutation mechanisms and frequency in crops is essential for genetic manipulation and breeding.
  • Paramutation offers potential for novel strategies in crop improvement.
  • Studying paramutation enhances our understanding of genome evolution and epigenetic inheritance.