Method with high-throughput screening potential for antioxidative substances using Escherichia coli biosensor katG'::lux
Related Experiment Video
Updated: Apr 4, 2026
High-throughput Screening and Biosensing with Fluorescent C. elegans Strains
Published on: May 19, 2011
Jenni Tienaho1, Tytti Sarjala2, Robert Franzén3
1Department of Chemistry and Bioengineering, Tampere University of Technology, Korkeakoulunkatu 8, FI-33101 Tampere, Finland; Natural Resources Institute Finland (Luke), Parkano Research Unit, Kaironiementie 15, FI-39700 Parkano, Finland.
Abstract:
A new method is described for the rapid real-time screening of antioxidative properties using a recombinant Escherichia coli DPD2511 biosensor. This microplate technique, without time-consuming pre-incubations and handling, has potential for a high-throughput search of bioactive compounds. Special emphasis was given to obtaining highly reliable and repeatable results.
