Related Experiment Video
Updated: Apr 4, 2026
07:10
Establishment of a Mouse Severe Acute Pancreatitis Model using Retrograde Injection of Sodium Taurocholate into the Biliopancreatic Duct
Published on: April 1, 2022
5.2K
Tamoxifen-induced acute pancreatitis - a case report
Rafał Czyżykowski1, Joanna Połowinczak-Przybyłek1, Anna Janiak1
1Klinika Chemioterapii Nowotworόw, Uniwersytet Medyczny w Łodzi.
Przeglad Menopauzalny = Menopause Review
|September 2, 2015
Summary
Tamoxifen, a breast cancer drug, can dangerously elevate triglycerides, leading to acute pancreatitis. Prompt drug withdrawal and conservative management improved the patient's condition.
Area of Science:
- Endocrinology
- Oncology
- Gastroenterology
Background:
- Tamoxifen is a selective estrogen receptor modulator (SERM) for hormone-receptor-positive breast cancer.
- SERMs exhibit tissue-specific agonist or antagonist activity.
- Tamoxifen can cause serious adverse events, including pancreatitis, and affects lipid metabolism by increasing triglycerides and very-low-density lipoprotein secretion.
