Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Thermoregulation01:26

Thermoregulation

3.1K
The human body has a sophisticated thermoregulation system that employs negative feedback mechanisms to maintain an optimal core temperature. When the core temperature drops, peripheral and central thermoreceptors send signals to the hypothalamus, activating the heat-promoting center. This center triggers several responses aimed at increasing the core temperature. First, vasoconstriction reduces the flow of warm blood from internal organs to the skin so that the heat is not lost from the skin,...
3.1K
Body Temperature01:25

Body Temperature

5.4K
The body's temperature, measured in degrees, is determined by the balance between heat production and dissipation to the surrounding environment. For instance, if exercising vigorously, the body will produce more heat, causing sweat and dissipating that heat. Despite extreme environmental conditions and physical exertion, the human temperature-control system maintains a constant core body temperature (the temperature of deep tissues, which are the tissues located beneath the skin and other...
5.4K
Body Temperature01:07

Body Temperature

1.8K
Body temperature reflects the equilibrium between heat production and heat loss within the body. Most heat is generated by metabolically active tissues, particularly the liver, heart, brain, kidneys, and endocrine organs. At rest, skeletal muscles contribute 20–30% of total heat production, but during vigorous exercise, this can increase up to 30–40 times.
The average body temperature is approximately 37°C (98.6°F) and typically ranges from 36.1–37.2°C...
1.8K
Mechanism of heat transfer01:19

Mechanism of heat transfer

2.3K
Understanding heat transfer mechanisms is essential for understanding how our bodies maintain balance in different environmental conditions. When the environment is thermoneutral, the body is in a state of balance, neither using nor releasing energy to maintain its core temperature. However, when the environment is not thermoneutral, the body employs four heat transfer mechanisms to maintain homeostasis: conduction, convection, evaporation, and radiation. These mechanisms facilitate heat...
2.3K
Thermosensation01:43

Thermosensation

35.5K
Peripheral thermosensation is the perception of external temperature. A change in temperature (on the surface of the skin and other tissues) is detected by a family of temperature-sensitive ion channels called Transient Receptor Potential, or TRP, receptors. These receptors are located on free nerve endings. Those detecting cold temperatures are closer to the surface of the skin than the nerve endings detecting warmth. These thermoTRP channels, while temperature selective, have relatively...
35.5K
Decreased Body Temperature01:29

Decreased Body Temperature

1.2K
A decreased body temperature can occur in patients with hypothermia and frostbite. Heat loss with extended cold exposure overpowers the body's ability to create heat, resulting in hypothermia. Core temperature readings help classify hypothermia. Mild hypothermia is temperatures between 32 °C (89.6 °F) and 35°C (95 °F) and is caused by impaired thermoregulation. Moderate hypothermia is temperatures between 28 C (82.4 °F) and 32 °C (89.6 °F) caused by...
1.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The 11th IUPS Workshop for Physiology Education: "Towards a new global horizon in the teaching of Physiology," Löwenstein, Germany, September 14-16, 2025.

Advances in physiology education·2026
Same author

Ultrasound technology as a tool to teach basic concepts of physiology and anatomy in undergraduate and graduate courses: a systematic review.

Advances in physiology education·2024
Same author

Impact of Peripheral Nerve Block Technique on Incidence of Phrenic Nerve Palsy in Shoulder Surgery.

Anesthesiology research and practice·2023
Same author

Ultrasound skills teaching in UK medical education: A systematic review.

The clinical teacher·2023
Same author

Bidirectional TRP/L Type Ca<sup>2+</sup> Channel/RyR/BK<sub>Ca</sub> Molecular and Functional Signaloplex in Vascular Smooth Muscles.

Biomolecules·2023
Same author

Ultrasound imaging in teaching cardiovascular physiology: disruption and challenge to foster learning.

Advances in physiology education·2022
Same journal

Medical Physiology Faculty Overpredict Assessment Question Complexity and Alignment with National Board Expectations.

Advances in physiology education·2026
Same journal

Correction for Kamel-ElSayed and Uhley, volume 48, 2024, p. 648-654.

Advances in physiology education·2026
Same journal

Cellular and network mechanisms of spreading depolarization.

Advances in physiology education·2026
Same journal

Figuring It Out: How I Became a Decent Anatomy Teacher in Three Hard Steps.

Advances in physiology education·2026
Same journal

A Low-Cost Metabolic Apparatus for Student Labs: Measuring Oxygen Consumption and Ventilation in Conscious Mice.

Advances in physiology education·2026
Same journal

Teaching Thyroid Physiology Through Art: An Integrative And Historical Pedagogical Approach.

Advances in physiology education·2026
See all related articles

Related Experiment Video

Updated: Apr 4, 2026

Measuring Skeletal Muscle Thermogenesis in Mice and Rats
07:56

Measuring Skeletal Muscle Thermogenesis in Mice and Rats

Published on: July 27, 2022

3.6K

Recent advances in thermoregulation.

Etain A Tansey1, Christopher D Johnson2

  • 1Centre for Biomedical Sciences Education, Queen's University, Belfast, Northern Ireland.

Advances in Physiology Education
|September 3, 2015
PubMed
Summary
This summary is machine-generated.

Thermoregulation maintains core body temperature for survival, crucial for physiological homeostasis. This review covers heat/cold stress responses, advanced detection, and control mechanisms like transient receptor potential channels.

Keywords:
brown adipose tissuecoldheatpreoptic area of the hypothalamusset pointthermoregulationtransient receptor potential channel

More Related Videos

Esophageal Heat Transfer for Patient Temperature Control and Targeted Temperature Management
06:43

Esophageal Heat Transfer for Patient Temperature Control and Targeted Temperature Management

Published on: November 21, 2017

25.3K
Field-Based Thermal Physiology Assay: Cold Shock Recovery under Ambient Conditions
07:54

Field-Based Thermal Physiology Assay: Cold Shock Recovery under Ambient Conditions

Published on: March 9, 2021

3.5K

Related Experiment Videos

Last Updated: Apr 4, 2026

Measuring Skeletal Muscle Thermogenesis in Mice and Rats
07:56

Measuring Skeletal Muscle Thermogenesis in Mice and Rats

Published on: July 27, 2022

3.6K
Esophageal Heat Transfer for Patient Temperature Control and Targeted Temperature Management
06:43

Esophageal Heat Transfer for Patient Temperature Control and Targeted Temperature Management

Published on: November 21, 2017

25.3K
Field-Based Thermal Physiology Assay: Cold Shock Recovery under Ambient Conditions
07:54

Field-Based Thermal Physiology Assay: Cold Shock Recovery under Ambient Conditions

Published on: March 9, 2021

3.5K

Area of Science:

  • Physiology
  • Homeostasis
  • Thermoregulation

Background:

  • Thermoregulation is vital for human survival, maintaining a core body temperature around 37°C.
  • It serves as a key example in teaching physiological homeostasis.
  • Understanding temperature regulation is essential for biology and clinical students.

Purpose of the Study:

  • To broadly review the thermoregulatory process.
  • Incorporate current advances in thermoregulation research.
  • Provide a comprehensive overview for students and professionals.

Main Methods:

  • Summarize fundamental thermoregulation concepts.
  • Assess physiological responses to thermal stress (heat and cold).
  • Review recent research on thermal detection and control mechanisms.

Main Results:

  • Physiological responses include vasodilation, vasoconstriction, sweating, nonshivering thermogenesis, piloerection, shivering, and behavioral changes.
  • Current research highlights thermal challenge detection, peripheral and central control mechanisms.
  • Includes the role of brown adipose tissue and transient receptor potential channels in temperature transduction.

Conclusions:

  • Presents an updated understanding of the neuroanatomic circuitry governing thermoregulation.
  • Integrates basic concepts with recent scientific discoveries.
  • Offers a comprehensive resource on human temperature regulation.