Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Clinical Trials01:16

Clinical Trials

11.2K
Clinical trials are prospective experimental studies conducted on humans to determine the safety and efficacy of treatments, drugs, diet methods, and medical devices. Using statistics in clinical trials enables researchers to derive reasonable and accurate conclusions from the collected data, allowing them to make wise decisions in uncertain situations. In medical research, statistical methods are crucial for preventing errors and bias.
There are four phases in a clinical trial. A phase one...
11.2K
The Scientific Method in Nursing Process01:18

The Scientific Method in Nursing Process

19.3K
The scientific method provides the foundation for any research. It is the most reliable and objective of all forms of gaining knowledge and guides in applying research-based evidence in practice and conducting future research.
When using research findings to change practice, one must understand the process used to guide a study. The scientific method is a systematic, step-by-step process that supports the data's validity, reliability, and generalizability. As a result, findings can be...
19.3K
Improving Translational Accuracy02:07

Improving Translational Accuracy

3.8K
3.8K
Improving Translational Accuracy02:07

Improving Translational Accuracy

15.5K
Base complementarity between the three base pairs of mRNA codon and the tRNA anticodon is not a failsafe mechanism. Inaccuracies can range from a single mismatch to no correct base pairing at all. The free energy difference between the correct and nearly correct base pairs can be as small as 3 kcal/ mol. With complementarity being the only proofreading step, the estimated error frequency would be one wrong amino acid in every 100 amino acids incorporated. However, error frequencies observed in...
15.5K
Clinical Trials: Overview01:11

Clinical Trials: Overview

5.4K
Clinical development focuses on how the drug will interact with the human body and encompasses four key phases of clinical trials, each serving a specific purpose in assessing the safety and effectiveness of new drugs. These phases overlap and build upon one another. Phase I involves a small group of healthy volunteers (typically 20-80 individuals) or, in cases where significant toxicity is expected, patients with the targeted disease, such as cancer or AIDS. The volunteers are tested for...
5.4K
Critical Thinking II01:25

Critical Thinking II

5.3K
Critical thinking is a cognitive process with several attributes. The attributes of critical thinking include the following:
5.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Patient Versus Prediction-Level Evaluation of a Dynamic Clinical Prediction Model of Sepsis.

Research square·2026
Same author

Patient Versus Prediction-Level Evaluation of a Dynamic Clinical Prediction Model of Sepsis.

medRxiv : the preprint server for health sciences·2026
Same author

Conducting multicenter trials through the trial innovation network comprehensive consultation.

Contemporary clinical trials·2026
Same author

Variation in Suicide Risk Screening by Pediatricians Across Subspecialties.

Pediatrics·2026
Same author

Behavioral and Mental Health Screening Practices, Barriers, and Facilitators: A National Survey of Pediatricians.

Academic pediatrics·2026
Same author

How Often do Youth ask Their Providers the Questions They Checked on an Attention-Deficit Hyperactivity Disorder Question Prompt List?

Journal of developmental and behavioral pediatrics : JDBP·2026

Related Experiment Video

Updated: Apr 4, 2026

Using Visual and Narrative Methods to Achieve Fair Process in Clinical Care
14:32

Using Visual and Narrative Methods to Achieve Fair Process in Clinical Care

Published on: February 16, 2011

25.0K

Applying Process Improvement Methods to Clinical and Translational Research: Conceptual Framework and Case Examples.

Denise H Daudelin1,2, Harry P Selker1,2, Laurel K Leslie1,2

  • 1Tufts Clinical and Translational Science Institute (CTSI), Tufts University, Boston, Massachusetts, USA.

Clinical and Translational Science
|September 3, 2015
PubMed
Summary

This study presents a Research Process Improvement Program framework to enhance efficiency in translational research. The program offers training and consultation to address common process issues, improving study completion.

Keywords:
clinical researchprocess improvementquality improvementrecruitment and retention

More Related Videos

The Participant-Reported Implementation Update and Score PRIUS: A Novel Method for Capturing Implementation-Related Data Over Time
06:05

The Participant-Reported Implementation Update and Score PRIUS: A Novel Method for Capturing Implementation-Related Data Over Time

Published on: February 19, 2021

1.8K
Working with Human Tissues for Translational Cancer Research
07:48

Working with Human Tissues for Translational Cancer Research

Published on: November 26, 2015

10.4K

Related Experiment Videos

Last Updated: Apr 4, 2026

Using Visual and Narrative Methods to Achieve Fair Process in Clinical Care
14:32

Using Visual and Narrative Methods to Achieve Fair Process in Clinical Care

Published on: February 16, 2011

25.0K
The Participant-Reported Implementation Update and Score PRIUS: A Novel Method for Capturing Implementation-Related Data Over Time
06:05

The Participant-Reported Implementation Update and Score PRIUS: A Novel Method for Capturing Implementation-Related Data Over Time

Published on: February 19, 2021

1.8K
Working with Human Tissues for Translational Cancer Research
07:48

Working with Human Tissues for Translational Cancer Research

Published on: November 26, 2015

10.4K

Area of Science:

  • Clinical and Translational Science
  • Health Services Research
  • Research Administration

Background:

  • Process improvement is recognized for enhancing quality and efficiency in translational research.
  • Frameworks for implementing such programs are not widely described.
  • Tufts CTSI developed a program to address this gap.

Purpose of the Study:

  • To present a framework for a Research Process Improvement Program.
  • To provide case examples of its implementation at Tufts CTSI.
  • To build capacity for efficient and timely clinical and translational studies.

Main Methods:

  • Developed online training seminars, workshops, and in-person consultations.
  • Taught core process improvement principles, methods, and tools.
  • Applied methods and relational coordination theory with researchers and support staff.

Main Results:

  • The program focused on capacity building for junior researchers, pilot awardees, and CTSI staff.
  • Addressed common process problems and quality gaps.
  • Aimed to improve the efficiency and success rate of translational studies.

Conclusions:

  • The presented framework offers a model for implementing research process improvement programs.
  • Capacity building is key to overcoming challenges in translational research.
  • Effective process improvement can lead to more timely and successful study completion.