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Related Concept Videos

Asthma-I: Introduction01:29

Asthma-I: Introduction

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Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
3.7K
Asthma: Pathogenesis and Management01:20

Asthma: Pathogenesis and Management

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Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
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Asthma-II: Pathophysiology and Classification01:26

Asthma-II: Pathophysiology and Classification

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Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
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Asthma-III: Symptoms and Complications01:24

Asthma-III: Symptoms and Complications

3.6K
Asthma, a common chronic respiratory condition, is classified considering the frequency and severity of symptoms alongside lung function impairment. Understanding this classification is essential for appropriate treatment and management. Here's a detailed look at the classification of asthma and its clinical features and complications:
Classification of Asthma
3.6K
Asthma-IV: Diagnostic and Management01:30

Asthma-IV: Diagnostic and Management

3.3K
The diagnosis and management of asthma are comprehensive, encompassing clinical assessments, lung function tests, and pharmacological interventions. Here's an overview:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
3.3K
Antiasthma Drugs: β2-Adrenoceptor Agonists01:25

Antiasthma Drugs: β2-Adrenoceptor Agonists

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Bronchodilators are critical in managing asthma, a chronic respiratory condition characterized by airway constriction due to inflammation and hyper-reactivity. Specifically, bronchodilators ease this constriction by relaxing the bronchial muscles, facilitating easier breathing.
One class of bronchodilators includes β2-adrenoceptor agonists. These agents target the β2-adrenoceptors located on bronchial smooth muscle cells. By stimulating these receptors, β2-agonists induce...
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Related Experiment Video

Updated: Apr 4, 2026

Murine Model of Allergen Induced Asthma
08:05

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Published on: May 14, 2012

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Asthma risk factors.

Elina Toskala1, David W Kennedy2

  • 1Department of Otorhinolaryngology-Head and Neck Surgery, Temple University, Philadelphia, PA.

International Forum of Allergy & Rhinology
|September 4, 2015
PubMed
Summary
This summary is machine-generated.

Childhood asthma is rising due to complex gene-environment interactions. Environmental factors like pollution and genetic susceptibility significantly increase asthma risk, highlighting an imbalance in modern living.

Keywords:
air pollutionallergensasthmaatopyenvironmental risk factorsepigeneticsgenetic risk factorshygiene hypothesismicrobesrisk factors

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Area of Science:

  • Pediatric respiratory health
  • Environmental medicine
  • Genetics of asthma

Background:

  • Childhood asthma prevalence is increasing globally, affecting 6-9% of children.
  • Asthma is a complex genetic disorder influenced by environmental factors, imposing significant societal burdens.
  • Despite research, the genetic basis of asthma remains incompletely understood.

Purpose of the Study:

  • To review risk factors for atopic and nonatopic asthma.
  • To examine environmental and genetic influences on asthma development in children and adults.

Main Methods:

  • Literature review of asthma risk factors.
  • Inclusion of environmental risk factors and genetic studies.

Main Results:

  • Environmental factors like air pollution, tobacco smoke, and occupational exposures increase asthma risk.
  • Atopy, stress, and obesity are identified as risk factors in genetically susceptible individuals.
  • Asthma results from a maladaptive gene-environment interaction, particularly during early life.

Conclusions:

  • The rising asthma prevalence suggests an imbalance between modern environments and human immunity, leading to inflammation.
  • Exposure to allergens and environmental factors triggers airway inflammation, contributing to the asthma and allergy epidemic.
  • Otolaryngologists should understand asthma's etiology, evaluation, and management due to its link with chronic rhinosinusitis.