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Updated: Apr 4, 2026

Metabolomic Analysis of Rat Brain by High Resolution Nuclear Magnetic Resonance Spectroscopy of Tissue Extracts
Published on: September 21, 2014
[IDENTIFICATION OF PHOSPHOETHANOLAMINE AND PHOSPHOSERINE IN THE BRAIN OF POND FISH PERCCOTTUS GLEHNI (ELEOTRIDAE,
Abstract:
Considerable modifications of the pools of free amino acid and some other compounds in the body ectothermic animals in response to the decrease in temperature are a consequence of the complexity of their adaptation mechanisms. There is no data in the literature on the contribution of such free connections in the low-temperature adaptation of brain ectothermic animals. In a previous study, it was found that as a result of exposure to acute cold shock in the brain eurothermal fish in large numbers appear two ninhydrinpositive compounds of unknown nature. In this paper, found that by the beginning of the winter period in the brain are accumulated the same connection also. Found that these are metabolites of phospholipids, phosphoethanolamine and phosphoserine. Phosphoethanolamine pool 94 times more in winter than in summer, and phosphoserine is only in the winter. Assumes that the accumulation of phosphoethanolamine and phosphoserine related to adaptation and modification of membrane phospholipid at low temperatures.

