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Serious Complications from Staphylococcal aureus in Atopic Dermatitis
Devika Patel1, Marla N Jahnke1
1Department of Dermatology, Henry Ford Hospital, Children's Hospital of Michigan, Detroit, Michigan.
Pediatric Dermatology
|September 5, 2015
Summary
Individuals with atopic dermatitis (AD) have higher rates of Staphylococcus aureus colonization. This can lead to rare but serious systemic infections like endocarditis, stroke, septic arthritis, and osteomyelitis.
Area of Science:
- Dermatology
- Infectious Diseases
- Microbiology
Background:
- Atopic dermatitis (AD) is associated with increased Staphylococcus aureus colonization.
- Impaired skin barrier in AD facilitates bacterial invasion and systemic spread.
- Staphylococcal superinfections pose serious health risks in AD patients.
Purpose of the Study:
- To report unusual cases of systemic Staphylococcus aureus infections in patients with atopic dermatitis.
- To review the literature on systemic complications of Staphylococcus aureus in AD.
- To raise awareness among practitioners about these rare but severe complications.
Main Methods:
- Case report of two patients with AD and severe systemic S. aureus infections.
- Extensive literature review of systemic Staphylococcus aureus complications in AD patients.
Main Results:
- Two cases presented with severe systemic illness: infective endocarditis with stroke, and septic arthritis with osteomyelitis.
- Literature review confirmed that while rare, systemic Staphylococcus aureus infections can occur in AD patients.
Conclusions:
- Systemic Staphylococcus aureus infections, though infrequent, are a potential severe complication in individuals with atopic dermatitis.
- Healthcare providers should maintain awareness of these risks in AD patients.
- Prompt recognition and management are crucial for favorable outcomes.
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