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Updated: Apr 4, 2026

Granulocyte-dependent Autoantibody-induced Skin Blistering
Published on: October 12, 2012
Oral mucosal involvement and petechial lesions: a SDRIFE case with unusual findings
Ayse Serap Karadag1, Emin Ozlu2, Necmettin Akdeniz2,3
1a Department of Dermatology , School of Medicine, Istanbul Medeniyet University , Istanbul , Turkey .
Abstract:
Symmetrical drug-related intertriginous and flexural exanthema (SDRIFE) is a type IV hypersensitivity reaction characterized by a symmetrical erythematous rash in the gluteal and intertriginous areas. SDRIFE was previously considered to be the same presentation as Baboon Syndrome, however, has been suggested to be a different entity in the recent publications. The lesions are generally maculopapular and there is no mucosal involvement. To date, no case with petechial findings and mucosal involvement has been reported in the literature. The present study reports a SDRIFE case with a symmetrical erythematous petechial rash and oral mucosal involvement after taking oral amoxicillin.
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