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Extracellular Glucose Depletion as an Indirect Measure of Glucose Uptake in Cells and Tissues Ex Vivo

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Transcultural Diabetes Nutrition Algorithm: Brazilian Application.

Fabio Moura¹, João Salles², Osama Hamdy³

¹Endocrinology and Metabolism Department, University of Pernambuco, Recife, Pernambuco 50100-130, Brazil. fmoura.pe@gmail.com.

|September 5, 2015

Summary

Obesity and type 2 diabetes (T2D) are rising in Brazil due to lifestyle changes. The transcultural Diabetes Nutrition Algorithm (tDNA-Brazil) offers a culturally adapted tool to help implement lifestyle changes for better health outcomes.

Keywords:

Brazil algorithm chronic non-communicable disease diabetes nutrition therapy obesity physical exercise prediabetes transcultural

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Multidisciplinary Approach to Obesity Management: A Case Report

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Published on: May 30, 2025

Area of Science:

Public Health
Endocrinology
Nutrition Science

Background:

Rising global prevalence of obesity, pre-diabetes, and type 2 diabetes (T2D), particularly in South America.
Brazil faces an exponential increase in these chronic non-communicable diseases, linked to dietary shifts, inactivity, and an aging population.
These health trends pose significant challenges to Brazilian public health and the healthcare system.

Purpose of the Study:

To introduce the transcultural Diabetes Nutrition Algorithm (tDNA) as a therapeutic tool for implementing lifestyle recommendations.
To present the culturally adapted Brazilian version, tDNA-Brazil, designed for clinical settings.
To improve disease-related outcomes through evidence-based, culturally adaptable interventions.

Main Methods:

The development of tDNA-Brazil considered Brazilian guidelines from the Brazilian Diabetes Association, Society of Cardiology, and Ministry of Health.
Incorporation of recommendations for nutrition therapy and structured physical exercise.
Focus on cultural adaptation for effective implementation in real-life clinical scenarios.

Main Results:

The tDNA-Brazil algorithm and its underlying recommendations are presented.
The tool aims to overcome clinical and personal challenges in lifestyle change implementation.
Designed to foster adherence and improve patient outcomes in managing T2D and related conditions.

Conclusions:

Lifestyle modifications, including nutrition therapy and physical activity, are crucial for preventing and treating obesity, pre-diabetes, and T2D.
The tDNA-Brazil provides a practical, evidence-based, and culturally sensitive approach to support these lifestyle changes.
Effective implementation of tDNA-Brazil can contribute to better management of chronic diseases in Brazil.