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BTK Signaling in B Cell Differentiation and Autoimmunity

Odilia B J Corneth1, Roel G J Klein Wolterink1, Rudi W Hendriks2

  • 1Department of Pulmonary Medicine, Erasmus MC Rotterdam, Room Ee2251a, PO Box 2040, NL 3000, CA, Rotterdam, The Netherlands.

Current Topics in Microbiology and Immunology
|September 6, 2015
PubMed
Summary

Bruton's tyrosine kinase (BTK) is vital for B cell development and function. Inhibiting BTK shows promise for treating B cell cancers and autoimmune diseases like lupus and rheumatoid arthritis.

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