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Hypertension and Asthma: A Comorbid Relationship
Sandra C Christiansen1, Michael Schatz2, Su-Jau Yang3
1Division of Rheumatology, Allergy and Immunology, University of California, San Diego, Calif; Division of Rheumatology, Allergy and Immunology, Veterans Affairs Medical Center, San Diego, Calif.
The Journal of Allergy and Clinical Immunology. in Practice
|September 7, 2015
Summary
Adult asthmatics with hypertension show increased asthma severity markers. This comorbidity is linked to higher short-acting beta-agonist use, emergency visits, and corticosteroid needs, indicating greater asthma morbidity.
Area of Science:
- Pulmonary Medicine
- Cardiovascular Medicine
- Epidemiology
Background:
- Hypertension is more prevalent in adult asthmatics.
- Limited data exists on hypertension's impact on asthma severity.
Purpose of the Study:
- To determine if hypertension affects asthma severity markers in adults.
- Investigate the association between comorbid hypertension and asthma exacerbations.
Main Methods:
- Retrospective case-control study of 117,922 adult asthmatics.
- Cases defined by high short-acting beta-agonist (SABA) use, emergency department visits/hospitalizations (EDHO), or corticosteroid dispensings (CCS).
- Logistic regression analyzed odds ratios for hypertension and asthma severity markers.
Main Results:
- Hypertension associated with increased odds of SABA > 6 (OR 1.19).
- Hypertension linked to higher odds of EDHO (OR 1.11) and CCS (OR 1.15).
- Findings adjusted for potential confounders.
Conclusions:
- Adult asthmatics with hypertension experience worse asthma morbidity.
- Comorbid hypertension is a significant factor in asthma severity.
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