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Updated: Apr 4, 2026

An Experimental Paradigm for the Prediction of Post-Operative Pain PPOP
Published on: January 27, 2010
Pain Associated With Cesarean Delivery Skin Closure: A Randomized Controlled Trial
A Dhanya Mackeen1, Adeeb Khalifeh, Jonah Fleisher
1Department of Obstetrics and Gynecology, Geisinger Health System, Danville, Pennsylvania; the Department of Biostatistics, Sidney Kimmel Medical College at Thomas Jefferson University, Philadelphia, Pennsylvania; New York University School of Medicine, New York, New York; and Yale School of Medicine, Obstetrics, Gynecology and Reproductive Sciences, New Haven, Connecticut.
Suture and staple skin closure after cesarean delivery showed no significant differences in patient-reported pain or pain medication use. This study supports suture closure for cesarean delivery incisions.
Area of Science:
- Obstetrics and Gynecology
- Surgical Innovation
- Patient Outcomes
Background:
- Cesarean delivery is a common surgical procedure.
- Skin closure methods, such as sutures and staples, are used to close surgical incisions.
- Understanding the impact of different closure methods on patient pain and medication use is crucial for optimizing postpartum recovery.
Purpose of the Study:
- To compare pain perception and pain medication use between women undergoing cesarean delivery with suture versus staple skin closure.
- To provide evidence-based recommendations for cesarean skin closure techniques.
Main Methods:
- Secondary analysis of a prospective, multicenter randomized clinical trial (2010-2012).
- Involved 746 women randomized to either suture (n=370) or staple (n=376) skin closure for low transverse cesarean incisions.
- Evaluated patient-reported pain scores and pain medication use during hospitalization and at 6 weeks postpartum.
Main Results:
- No significant differences in pain perception were found between suture and staple groups during hospitalization (median pain score 3.9 in both groups, P=.914) or 4-8 weeks postpartum (P=.949).
- Pain medication use was similar between groups, with no significant differences in intravenous morphine use during hospitalization (suture: 56 mg; staples: 54 mg, P=.545) or postpartum.
Conclusions:
- Suture and staple skin closure techniques for cesarean delivery result in comparable patient-reported pain and pain medication requirements.
- When considered with evidence of reduced wound morbidity with sutures, these findings support the use of suture closure for cesarean skin incisions.
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