Related Experiment Video
Updated: Apr 4, 2026

06:53
Modeling Primary Bone Tumors and Bone Metastasis with Solid Tumor Graft Implantation into Bone
Published on: September 9, 2020
3.4K
Extraskeletal Osteosarcoma Induced by a Foreign Body Granuloma
Jennifer E Slovak1, Nina R Kieves1, Joseph Haynes1
1From the Department of Veterinary Clinical Sciences (J.E.S., N.R.K.) and Department of Veterinary Pathology (J.H.), College of Veterinary Medicine, Iowa State University, Ames, IA.
Journal of the American Animal Hospital Association
|September 11, 2015
Summary
A retained surgical sponge caused a foreign body granuloma in an Italian greyhound, which progressed to extraskeletal osteosarcoma. This rare complication highlights the long-term risks of retained surgical materials in veterinary medicine.
Area of Science:
- Veterinary Pathology
- Surgical Complications
- Canine Oncology
Background:
- Foreign body granulomas can develop years after initial insult.
- Extraskeletal osteosarcomas are rare malignant tumors lacking bone origin.
- Retained surgical materials pose a risk for delayed complications.
Observation:
- An 8-year-old Italian greyhound presented with a large, cavitary cranial abdominal mass.
- Histopathology revealed extraskeletal osteosarcoma secondary to a foreign body granuloma.
- The granuloma was suspected to be from a surgical sponge retained from an ovariohysterectomy 7 years prior.
Findings:
- Diagnosis of extraskeletal osteosarcoma induced by foreign body granuloma.
- Identification of a retained surgical sponge as the likely inciting foreign body.
- Demonstration of a long latency period between foreign body retention and tumor development.
Implications:
- Foreign body granulomas can undergo malignant transformation.
- Retained surgical materials may lead to severe, delayed complications.
- Early detection and removal of foreign bodies are crucial to prevent adverse outcomes.

