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Infectious uveitis in Virginia.

Stephanie B Engelhard1, Zeina Haddad1, Asima Bajwa1

  • 1Department of Ophthalmology, University of Virginia, Charlottesville, VA, USA.

Clinical Ophthalmology (Auckland, N.Z.)
|September 11, 2015
PubMed
Summary
This summary is machine-generated.

Herpetic anterior uveitis, caused by varicella-zoster virus or herpes simplex virus, is the most common infectious uveitis, particularly in older adults. Prompt diagnosis and treatment are crucial for better visual outcomes in infectious uveitis patients.

Keywords:
chorioretinitisendophthalmitisinfectioustoxoplasmauveitis

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Area of Science:

  • Ophthalmology
  • Infectious Diseases
  • Immunology

Background:

  • Infectious uveitis is a significant cause of ocular inflammation and vision loss.
  • Understanding the epidemiology and causative agents of infectious uveitis is crucial for effective management.

Purpose of the Study:

  • To identify the causes, clinical characteristics, and outcomes of infectious uveitis.
  • To analyze patient demographics and visual acuity over time.

Main Methods:

  • Retrospective observational study.
  • Analysis of 491 uveitis patients from 1984 to 2014.
  • Inclusion of 77 patients diagnosed with infectious uveitis.

Main Results:

  • Herpetic anterior uveitis was the most common diagnosis (48.1%), primarily caused by varicella-zoster virus and herpes simplex virus.
  • Ocular toxoplasmosis and acute retinal necrosis (ARN) were also prevalent.
  • 50.6% of patients achieved visual acuity better than 20/40 at final follow-up, while 28.6% had vision worse than 20/200.

Conclusions:

  • Herpetic anterior uveitis is the leading cause of infectious uveitis in this population, especially in those over 60.
  • Ocular toxoplasmosis and ARN remain significant contributors to infectious uveitis.
  • Timely referral and treatment are essential for improving visual prognosis in infectious uveitis.