[Effect of pharmacotherapy on course of postoperative period after endovenous thermal ablation]

Area of Science:

• Vascular Surgery
• Pharmacology

Background:

• Endovenous thermal ablation (EVTA) is a common treatment for varicose veins.
• The postoperative period following EVTA can involve discomfort and complications.

Purpose of the Study:

• To evaluate the effect of micronized purified flavonoid fraction (MPFF) on the postoperative course after EVTA.
• To assess patient-reported outcomes and vein status post-EVTA with MPFF supplementation.

Main Methods:

• A prospective study comparing a control group with a group receiving MPFF for 7 days post-EVTA.
• Outcomes were assessed using CIVIQ, VCSS, and VAS questionnaires, alongside ultrasound angioscanning.
• Statistical analysis was performed using Statistica 6.0 and Student's t-test.

Main Results:

• Both groups achieved complete and stable obliteration of target veins.
• No statistically significant differences were observed in CIVIQ and VCSS scores between groups at the final examination.
• Minor, non-statistically significant differences in questionnaire scores were noted between days 2-14 post-EVTA.

Conclusions:

• MPFF did not demonstrate a statistically significant benefit in the studied postoperative parameters after EVTA.
• Phlebotrophic therapy, including MPFF, may help reduce phlebitic alterations and improve patient quality of life post-EVTA.