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Updated: Apr 4, 2026

Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems
Published on: June 13, 2025
Evidence-Informed, Evidence not Used: A Pilot Study of a Sustained Flawed Process and Unfinished Business
Stan-Shlomo Einstein1, Shulamith Lala Ashenberg Straussner2, Timothy P Johnson3
1a 1 Middle Eastern Summer Institute on Drug Use (MESIDU) , Jerusalem , Israel.
Abstract:
An anonymous, online survey using a convenience sample of global researchers was implemented during 2013-2014 to explore the actual use or nonuse of their research outcomes in a range of interventions in the area of substance use and related disorders. Eighty-seven researchers from 19 countries responded. Based on their self-reports, the utilizability of their findings were either unknown to them or had no effects in terms of substance use treatment, prevention, policies, or professional education. Most respondents did believe, however, that their investigations had an influence on substance use research. The study's limitations are noted.
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