Related Experiment Video
Updated: Jul 13, 2026
06:16
Involving Individuals with Developmental Language Disorder and Their Parents/Carers in Research Priority Setting
Published on: June 6, 2020
Research Priority Setting Exercises in Neglected Tropical Diseases: A Systematic Mapping Review.
Manish Barik1, Sushree Nibedita Panda2, Gooty Shirisha3
1, New Delhi, India. manishbarik2.bbsr@gmail.com.
Journal of Epidemiology and Global Health
|July 11, 2026
Summary
Research priority-setting for neglected tropical diseases (NTDs) is expanding but lacks standardization. Key priorities include health systems, community engagement, and equity-focused implementation research to guide global NTD targets.
Area of Science:
- Global Health
- Tropical Medicine
- Research Policy
Background:
- Neglected tropical diseases (NTDs) impact over 1.7 billion people globally, predominantly in low- and middle-income countries.
- Despite their significant burden, NTDs suffer from underfunding and fragmented research efforts.
- Systematic research priority-setting is crucial for aligning limited resources with critical needs.
Purpose of the Study:
- To systematically map published research priority-setting exercises for NTDs.
- To synthesize the methodologies, stakeholder involvement, and thematic priorities identified in these exercises.
Main Methods:
- A systematic mapping review of studies from PubMed, EMBASE, and Web of Science up to March 28, 2025.
- Inclusion criteria: studies explicitly reporting research prioritization for at least one WHO-listed NTD.
- Data extraction and descriptive analysis of study design, scope, methods, stakeholders, and outcomes, with priorities classified into six domains.
Main Results:
- Fifteen studies met the inclusion criteria, predominantly mixed-methods and conducted at country or regional levels.
- Delphi was the most common prioritization framework; broad stakeholder engagement was reported, including clinicians, policymakers, researchers, NGOs, and vulnerable populations.
- Lymphatic filariasis, soil-transmitted helminths, and schistosomiasis were frequently prioritized NTDs, with key research themes including health system strengthening, community engagement, and equity-oriented implementation research.
Conclusions:
- Research priority-setting for NTDs has grown but shows heterogeneity in methods and inclusivity.
- A caution against prioritizing only high-prevalence NTDs is advised to avoid overlooking less common diseases and affected populations.
- Six cross-cutting research priority domains align with the WHO NTD Roadmap and can guide future research agendas and policy implementation.
Related Concept Videos
01:21Antiprotozoal Agents
Leishmaniasis is a widespread parasitic disease caused by several Leishmania species. It affects millions of people each year and remains a major public health problem in endemic regions. First-line treatment relies on pentavalent antimonials, including meglumine antimoniate and sodium stibogluconate. Even so, how these drugs work has not been fully clear, especially their interaction with parasite-specific biochemical pathways. One key target is trypanothione reductase (TR), an enzyme that...
01:26Principles of Disease Surveillance
Disease surveillance is the systematic collection, analysis, and interpretation of health data essential to the planning, implementation, and evaluation of public health practice. This process integrates data dissemination to entities responsible for preventing and controlling disease, injury, and disability. Surveillance systems provide crucial information for action, helping public health authorities make informed decisions to manage and prevent outbreaks, ensure public safety, optimize...
01:30Leishmaniasis
Leishmaniasis is a protozoal disease caused by species of the genus Leishmania and transmitted through the bite of infected female sandflies. The parasite exists in two principal morphological forms during its life cycle. A sandfly acquires intracellular amastigotes from an infected reservoir host, such as a dog. Within the sandfly, these forms differentiate into motile, flagellated promastigotes. During a subsequent blood meal, promastigotes are injected into the human host, where they...
01:26Methods Of Healthcare Delivery System
At the different levels of the healthcare system, we see varying methods of healthcare used. These methods include managed care systems, case management, and primary healthcare.
Managed Care System:
The managed care system is designed to control the cost while maintaining the quality of care. The patient's care from admission to discharge is planned by the primary care provider or the case manager, also known as the gatekeeper. In a managed care system, the number of care providers is limited...
Managed Care System:
The managed care system is designed to control the cost while maintaining the quality of care. The patient's care from admission to discharge is planned by the primary care provider or the case manager, also known as the gatekeeper. In a managed care system, the number of care providers is limited...
01:28Infectious Diseases and Their Occurrence
Infectious diseases appear in populations through various transmission patterns, influenced by pathogen characteristics, population immunity, environmental conditions, and social behavior. Understanding these patterns is essential for effective public health surveillance and intervention. These categories—sporadic, outbreak, epidemic, pandemic, and endemic—help frame the nature and scope of disease events.Sporadic diseases occur irregularly and infrequently, without a predictable temporal or...
01:22American Trypanosomiasis
Chagas disease, or American trypanosomiasis, is a vector-borne parasitic infection caused by Trypanosoma cruzi, a flagellated protozoan (kinetoplastid) of the family Trypanosomatidae. The disease is endemic in Latin America, although cases are increasingly reported worldwide due to human migration. Transmission most commonly occurs when feces of infected triatomine bugs contaminate bite wounds or mucosal surfaces; additional routes include congenital, transfusional, transplant-related, and oral...