Weight regaining: From statistics and behaviors to physiology and metabolism
Costas A Anastasiou1, Eleni Karfopoulou1, Mary Yannakoulia1
1Department of Nutrition and Dietetics, Harokopio University, Athens, Greece.
Abstract:
Achieving maintenance of weight loss is crucial to combat obesity. However, most individuals tend to regain weight. Data from successful maintainers show that they remain vigilant and constantly apply techniques to oppose the course of regaining. On the other hand, current advances in obesity research show that the reduced obese state is a state of altered physiology in terms of energy balance. This review describes the physiological adaptations occurring after weight loss that predispose to regaining. Specifically, changes regarding body composition, hormonal background, energy expenditure and control of food intake are discussed. Moreover, metabolites that can act as regain predictors and dietary techniques to oppose regaining are presented.
Related Concept Videos
Metabolic States of the Body: The Absorptive State
Energy Balance
Metabolic States of the Body: The Postabsorptive State
Initially, glycogen stored in the liver is broken down to release glucose into the bloodstream, while glycogen in the muscles is broken down to supply glucose for energy directly within the muscle cells. As glycogen stores diminish,...
Muscle Recovery and Fatigue
Pharmacokinetics in Obese Patients: Drug Metabolism and Excretion
Overview of Protein Metabolism
Amino acids play various roles in the body once they are absorbed into cells. They are restructured...


