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    We developed a novel two-dimensional phase unwrapping technique using inverse problem minimization. This method offers rotation invariance, improving unwrapping accuracy for a wider range of images in quantitative phase evaluation.

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    Area of Science:

    • Image processing
    • Computational imaging
    • Optical metrology

    Background:

    • Phase unwrapping is crucial for quantitative phase imaging.
    • Existing methods struggle with complex phase data and rotation.
    • Tomographic phase microscopy generates wrapped phase images requiring unwrapping.

    Purpose of the Study:

    • To introduce a new, rotation-invariant 2D phase unwrapping technique.
    • To improve the accuracy and applicability of quantitative phase evaluation.
    • To address limitations of current phase unwrapping algorithms.

    Main Methods:

    • Formulating phase unwrapping as an inverse problem.
    • Minimizing an energy functional with weighted data fidelity and higher-order total variation regularization.
    • Implementing a rotation-invariant algorithm.

    Main Results:

    • The proposed method successfully unwraps phase from simulated and real tomographic phase microscope data.
    • Demonstrated superior performance compared to state-of-the-art methods, particularly in handling complex phase distributions.
    • Achieved rotation invariance, expanding the range of applicable images.

    Conclusions:

    • The new technique significantly enhances 2D phase unwrapping capabilities.
    • It broadens the applicability and outreach of quantitative phase evaluation methods.
    • This approach offers a robust solution for challenging phase imaging scenarios.