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Two Case Reports of Group B Streptococcal Infective Endocarditis Complicated by Embolism

Rie Aoyama1, Ayumi Kobayashi, Yusuke Tubokou

  • 1Department of Cardiology, Tokyo Metropolitan Geriatric Hospital, Japan.

Internal Medicine (Tokyo, Japan)
|September 16, 2015
PubMed

Insights

Group B Streptococcus (GBS) infective endocarditis (IE) is rare but serious, often causing aortic embolism. Early surgery for large, mobile vegetations is crucial for better outcomes in GBS IE cases.

Area of Science:

  • Infectious Diseases
  • Cardiology
  • Bacteriology

Background:

  • Streptococcus agalactiae (Group B Streptococcus, GBS) is a significant perinatal pathogen.
  • GBS infections are increasingly reported in non-pregnant adults.
  • GBS infective endocarditis (IE) is an uncommon but severe manifestation.

Observation:

  • Two cases of GBS IE are presented.
  • Case 1: Mobile aortic valve vegetation led to an infective cerebral aneurysm.
  • Case 2: Patient presented with an acute aortic embolic event.

Findings:

  • GBS IE is characterized by a severe clinical course and specific vegetation properties.
  • Large, mobile vegetations are a key indicator for intervention.
  • Current guidelines suggest early surgery for large mobile vegetations (Class IIb).

Implications:

  • Early surgical intervention should be strongly considered for GBS IE, especially with large mobile vegetations.
  • This approach may improve patient outcomes in severe GBS IE.
  • Further research into optimal management strategies for GBS IE is warranted.

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