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Related Concept Videos

Probiotics01:22

Probiotics

221
Probiotics are live, non-pathogenic microorganisms that confer health benefits by modulating the gut microbiota. The human gastrointestinal tract harbors a complex microbial ecosystem, and the balance of this microbiota is crucial for digestive and systemic health. Among the most extensively studied and utilized probiotics are species formerly classified within the genera Lactobacillus and Bifidobacterium. These organisms not only naturally colonize the human gut but are also consumed through...
221
Development of Human Microbiota01:30

Development of Human Microbiota

36
The human microbiota begins developing at birth and undergoes continual change as we age. Infancy marks a critical period of microbial sensitivity, offering a “window of opportunity” during which beneficial microbes help mature the immune system. By age three, children typically develop a more stable and diverse microbial community. Newborns acquire microbes from their immediate environment; vaginal delivery favors maternal vaginal microbes, while cesarean births favor microbes from...
36
Microbiota of the Large Intestine01:27

Microbiota of the Large Intestine

50
The large intestine hosts the most densely populated microbial ecosystem in the human body. This complex community primarily consists of anaerobic bacteria, with Bacillota (formerly Firmicutes) and Bacteroidota (formerly Bacteroidetes) as the predominant groups. The distribution of these microbes varies along different sections of the large intestine, influenced by local environmental factors such as oxygen availability and nutrient composition.The cecum, located at the beginning of the large...
50
Functions of the Gut Microbiota01:18

Functions of the Gut Microbiota

54
The gut microbiota includes trillions of microorganisms that colonize the human gastrointestinal tract, including bacteria, archaea, viruses, and fungi. This complex ecosystem plays a critical role in maintaining intestinal and systemic health. Most of these microbes inhabit the large intestine, establishing a relatively stable and diverse community that contributes to gut homeostasis through various metabolic, immunological, and protective mechanisms.Dominant bacterial phyla, such as...
54
Microbiota of the Stomach and Small Intestine01:27

Microbiota of the Stomach and Small Intestine

43
The human gastrointestinal (GI) tract is characterized by distinct physicochemical conditions that shape its microbial communities. Among these, the stomach presents a particularly challenging environment for microbial colonization due to its highly acidic pH, ranging from 1 to 3. This extreme acidity effectively limits microbial density. However, certain acid-tolerant microorganisms are capable of surviving in this niche. Notably, Helicobacter pylori can colonize the gastric mucosa,...
43
Introduction to the Human Microbiota01:22

Introduction to the Human Microbiota

79
Microorganisms colonize various regions of the human body, including the mouth, nasal passages, throat, stomach, intestines, urogenital tract, and skin. The total number of microbial cells is estimated to range from 10¹³ to 10¹⁴—comparable to, or exceeding, the number of human somatic cells. This host–microbiome relationship has led to the conceptualization of humans as supraorganisms, wherein microbial communities perform vital roles in development, immunity,...
79

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Related Experiment Video

Updated: Apr 3, 2026

An In Vitro Batch-culture Model to Estimate the Effects of Interventional Regimens on Human Fecal Microbiota
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Intestinal Microbiota, Obesity and Prebiotics.

R Barczynska, K Bandurska, K Slizewska

    Polish Journal of Microbiology
    |September 17, 2015
    PubMed
    Summary
    This summary is machine-generated.

    Gut microbiota and prebiotics are crucial for maintaining a healthy body weight. Research explores their role in preventing and treating obesity, offering new therapeutic strategies.

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    Area of Science:

    • Microbiology
    • Nutrition Science
    • Obesity Research

    Background:

    • Obesity prevalence has significantly increased globally in children and adults.
    • Obesity development involves complex environmental and genetic factors.
    • Intestinal microorganisms are increasingly recognized for their role in weight regulation.

    Purpose of the Study:

    • To investigate the role of gut microbiota and prebiotics in maintaining healthy body weight.
    • To explore the potential of gut microbiota modulation for obesity prevention and treatment.
    • To assess the gut microbiota as a potential biomarker for obesity predisposition.

    Main Methods:

    • Literature review of studies on gut microbiota composition and function.
    • Analysis of research on prebiotic interventions and their impact on weight.
    • Examination of data linking gut microbial profiles to obesity risk.

    Main Results:

    • Gut microbiota plays a significant role in energy homeostasis and host metabolism.
    • Prebiotics can modulate gut microbiota composition, influencing satiety and fat storage.
    • Alterations in gut microbial diversity and function are associated with obesity.

    Conclusions:

    • Modulating the gut microbiota through prebiotics offers a promising avenue for obesity management.
    • Targeting the gut microbiome may provide novel strategies for preventing and treating obesity.
    • Further research is needed to fully elucidate the gut microbiota's role as a biomarker for obesity.