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Published on: December 8, 2016
Rapid Cell Patterning Induced by Differential Topography on Silica Nanofractal Substrates
Guannan Li1,2, Gao Yang1,2, Pengchao Zhang1,2
1Beijing National Laboratory for Molecular Sciences (BNLMS), Key Laboratory of Organic SolidsInstitute of Chemistry, Chinese Academy of Sciences, Beijing, 100190, P. R. China.
Abstract:
Predesigned silica nanofractal substrates are utilized for rapid cell patterning, based on differential cell adhesion originating from surface topographic interactions. Cell patterns with various shapes are successfully formed, from simple geometrical shapes to a complex "CELL" symbol. This study assists understanding of cell-substrate interactions and facilitates biological applications.

