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Right ventricular and atrial functions in patients with nonischemic dilated cardiomyopathy

Kursat Tigen1, Tansu Karaahmet2, Cihan Dundar3

  • 1Department of Cardiology, Marmara University Faculty of Medicine, Fevzi Cakmak Mahallesi, Muhsin Yazicioglu Caddesi, No: 10, Istanbul, Pendik, Turkey.

Wiener Klinische Wochenschrift
|September 18, 2015
PubMed

Insights

Right ventricular systolic function is impaired in nonischemic dilated cardiomyopathy. Two-dimensional speckle tracking echocardiography effectively assesses right ventricular and atrial function in these patients.

Area of Science:

  • Cardiology
  • Echocardiography
  • Cardiac Imaging

Background:

  • Nonischemic dilated cardiomyopathy (DCM) often involves impaired right ventricular (RV) and right atrial (RA) function.
  • Novel echocardiographic measures are needed to accurately assess RV and RA function in DCM.

Purpose of the Study:

  • To evaluate RV and RA functions in patients with nonischemic DCM using advanced echocardiographic techniques.
  • To identify echocardiographic parameters that predict RV systolic dysfunction in this population.

Main Methods:

  • Included 40 nonischemic DCM patients and 26 healthy controls.
  • Assessed cardiac function using tissue Doppler imaging (TDI) and 2D speckle tracking echocardiography (STE).
  • Defined moderate to severe RV systolic dysfunction as tricuspid lateral annulus systolic velocity < 9 cm/s.

Main Results:

  • DCM patients with RV systolic dysfunction showed significantly reduced RV longitudinal strain and RA function by STE.
  • RV free wall basal segment longitudinal strain predicted RV systolic dysfunction with 72% sensitivity and 73% specificity (AUC: 0.793).
  • Reduced LV systolic velocity and strain were also observed in patients with RV systolic dysfunction.

Conclusions:

  • RV systolic function is compromised in nonischemic DCM.
  • 2D STE is a promising noninvasive tool for assessing RV and RA function in nonischemic DCM patients.
Abstract

Keywords:
Nonischemic dilated cardiomyopathyRight atrial functionRight ventricular functionSpeckle tracking echocardiographyTissue Doppler imaging

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