Bilateral multiple intrapulmonary nodules: a puzzled and rare disease

Area of Science:

• Thoracic oncology
• Pathology
• Surgical oncology

Background:

• Primary intrapulmonary spindle cell thymomas (PISCT) are rare lung neoplasms.
• PISCT are considered a subtype of primary intrapulmonary thymomas (PIT).
• These lesions can be misdiagnosed as various epithelial or mesenchymal tumors.

Purpose of the Study:

• To report the first case of bilateral, multiple primary intrapulmonary spindle cell thymomas.
• To describe the diagnostic and management experience for this unique presentation.
• To contribute to the understanding of rare thymic tumors in the lung.

Main Methods:

• Case presentation of a patient with bilateral multiple PISCT.
• Review of diagnostic imaging and histopathological findings.
• Description of the treatment approach and clinical course.

Main Results:

• Successful diagnosis and management of a unique case of bilateral multiple PISCT.
• Histopathological confirmation of PISCT.
• The case presented a novel finding in the literature regarding PISCT.

Conclusions:

• Bilateral, multiple PISCT is a rare entity, previously unreported.
• This case highlights the importance of considering PISCT in the differential diagnosis of lung masses.
• The successful management provides valuable experience for clinicians dealing with similar rare pulmonary tumors.