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Endoplasmic reticulum stress implicated in chronic traumatic encephalopathy

Brandon P Lucke-Wold1,2, Ryan C Turner1,2, Aric F Logsdon2,3

  • 1Department of Neurosurgery, West Virginia University School of Medicine;

Journal of Neurosurgery
|September 19, 2015
PubMed
Abstract

Keywords:
ATF6 = activating transcription factor 6BiP = binding immunoglobulin proteinCHOP = C/EBP homology proteinCTE = chronic traumatic encephalopathyDAB = diaminobenzidineDHA = docosahexaenoic acidER = endoplasmic reticulumGADD34 = growth arrest and DNA damage-inducible protein 34GSK3β = glycogen synthase kinase-3βIHC = immunohistochemistryIRE1α = inositol requiring enzyme 1αJNK = c-Jun N-terminal kinaseNFL = National Football LeaguePBS = phosphate-buffered salinePERK = protein kinase RNA-like ER kinasePHF = paired helical filamentTBI = traumatic brain injuryWWE = World Wrestling EntertainmentXBP1 = X-box binding protein 1blast traumatic brain injurychronic traumatic encephalopathydocosahexaenoic acidendoplasmic reticulum stresshyperphosphorylated taup-eIF2a = phosphorylated eukaryotic initiation factor 2αtrauma

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