Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

True Stress and True Strain01:28

True Stress and True Strain

858
Engineering stress is calculated as the load divided by the original, undeformed cross-sectional area. It approximates a material under load. This approximation is especially relevant post-yield in ductile materials. Though engineering stress-strain diagrams are often used for their convenience and accessibility, they can sometimes fall short in accuracy, particularly when dealing with large strain values.
In contrast, true stress offers a more precise portrayal. It is computed by dividing the...
858
False Memories01:18

False Memories

491
False memories represent a cognitive distortion in which individuals recall events that did not happen, or remember them in an altered form. This phenomenon highlights the brain's constructive nature in processing and recalling memories, emphasizing that memory is not a perfect representation of past events but rather a dynamic reconstruction influenced by various factors.
One primary source of false memories is misattribution, where individuals incorrectly associate external information...
491
Long-term Depression01:05

Long-term Depression

33.3K
Long-term depression, or LTD, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTD is the process of synaptic weakening that occurs over time between pre and postsynaptic neuronal connections. The synaptic weakening of LTD works in opposition to synaptic strengthening by long-term potentiation (LTP) and together are the main mechanisms that underlie learning and memory.
33.3K
Long-term Depression01:03

Long-term Depression

3.4K
Long-term depression, or LTD, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTD is the process of synaptic weakening that occurs over time between pre and postsynaptic neuronal connections. The synaptic weakening of LTD works in opposition to synaptic strengthening by long-term potentiation (LTP) and together are the main mechanisms that underlie learning and memory.
Calcium Ion Concentration Mechanism
If over...
3.4K
Freezing Point Depression and Boiling Point Elevation03:12

Freezing Point Depression and Boiling Point Elevation

40.4K
Boiling Point Elevation
The boiling point of a liquid is the temperature at which its vapor pressure is equal to ambient atmospheric pressure. Since the vapor pressure of a solution is lowered due to the presence of nonvolatile solutes, it stands to reason that the solution’s boiling point will subsequently be increased. Vapor pressure increases with temperature, and so a solution will require a higher temperature than will pure solvent to achieve any given vapor pressure, including one...
40.4K
Depressants01:28

Depressants

462
Depressant drugs, including alcohol and sedative-hypnotics, diminish central nervous system activity by enhancing the action of gamma-aminobutyric acid (GABA), a neurotransmitter that reduces brain activity and promotes relaxation. These substances can have various therapeutic uses but also pose significant risks, especially when misused or combined.
Alcohol is a common depressant that can induce a sense of relaxation and reduced inhibition at low doses. Contrary to its occasional...
462

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Blood Alcohol Concentration in Finnish Suicide Deaths and Associated Risk Factors, 2016-2024.

Acta psychiatrica Scandinavica·2026
Same author

Effects of Nature-based Group Intervention on Cognition and Nature Connectedness Among Lonely Older Adults Living in Assisted Living Facilities-Secondary Analyses of an RCT.

Journal of the American Medical Directors Association·2026
Same author

The role of recovery from work and work-life spillover in the association between chronotype and mental health problems: A population-based study.

Sleep health·2026
Same author

UVA1 exposures change gene expression and circadian time-related protein CRY2 in human skin.

Journal of photochemistry and photobiology. B, Biology·2026
Same author

Effectiveness of nature-based group intervention in loneliness and health-related quality-of-life in lonely older adults living in assisted living facilities-a randomised controlled trial.

Age and ageing·2026
Same author

Longitudinal associations of meteorological parameters during winter months in Sweden with self-reported symptoms of anxiety in the spring.

International journal of biometeorology·2026

Related Experiment Video

Updated: Feb 11, 2026

Infrared Thermography for the Detection of Changes in Brown Adipose Tissue Activity
08:16

Infrared Thermography for the Detection of Changes in Brown Adipose Tissue Activity

Published on: September 28, 2022

2.9K

Brown fat activity deepens depression: True or false?

Timo Partonen1

  • 1a National Institute for Health and Welfare , Department of Health , Helsinki , Finland.

Annals of Medicine
|September 19, 2015
PubMed
Summary
This summary is machine-generated.

Circadian clocks use a slowing-down mechanism influenced by temperature. Brown adipose tissue activity may disrupt this, potentially linking to mood disorders and increased suicide risk during puberty.

Keywords:
Behaviorcircadiancryptochromediurnalmoodseasonalsuicidetemperature

More Related Videos

Whole Body and Regional Quantification of Active Human Brown Adipose Tissue Using 18F-FDG PET/CT
10:30

Whole Body and Regional Quantification of Active Human Brown Adipose Tissue Using 18F-FDG PET/CT

Published on: April 1, 2019

9.5K
Functional Imaging of Brown Fat in Mice with 18F-FDG micro-PET/CT
10:53

Functional Imaging of Brown Fat in Mice with 18F-FDG micro-PET/CT

Published on: November 23, 2012

19.8K

Related Experiment Videos

Last Updated: Feb 11, 2026

Infrared Thermography for the Detection of Changes in Brown Adipose Tissue Activity
08:16

Infrared Thermography for the Detection of Changes in Brown Adipose Tissue Activity

Published on: September 28, 2022

2.9K
Whole Body and Regional Quantification of Active Human Brown Adipose Tissue Using 18F-FDG PET/CT
10:30

Whole Body and Regional Quantification of Active Human Brown Adipose Tissue Using 18F-FDG PET/CT

Published on: April 1, 2019

9.5K
Functional Imaging of Brown Fat in Mice with 18F-FDG micro-PET/CT
10:53

Functional Imaging of Brown Fat in Mice with 18F-FDG micro-PET/CT

Published on: November 23, 2012

19.8K

Area of Science:

  • Chronobiology
  • Metabolic physiology
  • Neuroendocrinology

Background:

  • Circadian clocks possess an intrinsic slowing-down mechanism.
  • Organismal temperature regulation, particularly heat generation by brown adipose tissue, is a fundamental time-giver.
  • Core body temperature rhythms are guided by brown adipose tissue activity.

Discussion:

  • Cryptochrome proteins are crucial for adapting circadian rhythms to temperature cues.
  • Dysfunctional cryptochromes may increase the brain's sensitivity to brown adipose tissue activity.
  • This heightened sensitivity could impair the circadian clock's slowing-down function.

Key Insights:

  • Brown adipose tissue's heat generation may interfere with the circadian clock's natural slowing.
  • Compromised circadian rhythmicity is implicated in the development of mood disorders.
  • These mechanisms may contribute to increased suicide mortality observed during puberty.

Outlook:

  • Further research into cryptochrome function and temperature entrainment is warranted.
  • Investigating the link between brown adipose tissue, circadian disruption, and pubertal mood disorders is crucial.
  • Therapeutic strategies targeting circadian rhythm regulation could mitigate mood disorder risks.