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Preventative effect of ondansetron on postanesthesia shivering in children undergoing caudal anesthesia: a randomized

Hongfei Lin1, Jiangmei Wang1, Ziying Jin1

  • 1Department of Anesthesiology, The Children's Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.

Pediatric Research
|September 19, 2015
PubMed

Insights

Ondansetron effectively reduced postanesthesia shivering in children who received caudal anesthesia. This study confirms ondansetron

Area of Science:

  • Anesthesiology
  • Pediatric Anesthesia
  • Pharmacology

Background:

  • Postanesthesia shivering is a common complication in children.
  • Ondansetron's efficacy in reducing shivering in adults is known.
  • Limited research exists on ondansetron for pediatric postanesthesia shivering.

Purpose of the Study:

  • To investigate the effectiveness of ondansetron in preventing postanesthesia shivering in children undergoing caudal anesthesia.
  • To evaluate ondansetron's impact on shivering severity and incidence in pediatric patients.

Main Methods:

  • A randomized controlled trial involving 59 children aged 8-13 years.
  • Children received either ondansetron (4 mg IV) or normal saline post-anesthesia.
  • Physiological parameters and shivering scores were monitored.

Main Results:

  • Ondansetron significantly decreased the likelihood of postanesthesia shivering.
  • A notable reduction in shivering score over time was observed in the ondansetron group.
  • No adverse effects were mentioned in the abstract.

Conclusions:

  • Ondansetron is effective in reducing postanesthesia shivering in children.
  • This finding supports the use of ondansetron for pediatric patients receiving caudal and intravenous anesthesia.
  • Further research may explore optimal dosing and long-term effects.
Abstract

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