Nasal bacterial colonization in cases of idiopathic epistaxis in children

Payal Kamble1, Sonal Saxena2, Sunil Kumar1

  • 1Department of Otorhinolaryngology-Head & Neck Surgery, Lady Hardinge Medical College & Associated Hospitals Shaheed Bhagat Singh Marg, New Delhi 110001, India.

Insights

Nasal Staphylococcus aureus colonization is linked to idiopathic epistaxis in children. This bacterial presence contributes to nasal inflammation, crusting, and bleeding, highlighting its role in pediatric nosebleeds.

Area of Science:

  • Pediatric Otolaryngology
  • Microbiology
  • Nasal Pathophysiology

Background:

  • Idiopathic epistaxis is common in children.
  • The underlying causes of recurrent nosebleeds are not always clear.
  • Nasal bacterial colonization is a potential contributing factor.

Purpose of the Study:

  • To investigate the association between nasal bacterial colonization and idiopathic epistaxis in pediatric patients.
  • To identify specific bacterial species involved in pediatric epistaxis.

Main Methods:

  • A descriptive, hospital-based observational study.
  • 112 pediatric patients (ages 4-16) were divided into control (no epistaxis) and epistaxis groups.
  • Anterior nasal cavity swabs were collected for microbiological evaluation.

Main Results:

  • A significant association was found between nasal Staphylococcus aureus colonization and idiopathic epistaxis.
  • S. aureus colonization correlated with increased crusting and dilated blood vessels in the nasal septum of epistaxis patients.

Conclusions:

  • Nasal Staphylococcus aureus colonization initiates pathological events including inflammation, crusting, and neovascularization.
  • These changes can lead to nasal irritation, digital trauma, and subsequent epistaxis in children.
  • S. aureus plays a significant role in the etiology of idiopathic epistaxis in pediatric populations.
Abstract

Related Concept Videos

Epistaxis01:30

Epistaxis

Epistaxis, or nosebleeds, occurs when small, swollen blood vessels in the nasal mucous membrane rupture. Typically, the anterior septum is the primary site of occurrence.
Etiology
Possible causes of this condition include high blood pressure, trauma, low humidity, upper respiratory tract infections, allergies, foreign bodies, nasal inhalation of corticosteroids or illicit drugs, excessive use of decongestant nasal sprays, facial or nasal surgery, anatomic malformation, tumors, or systemic...
732
Microbiota of the Respiratory Tract01:29

Microbiota of the Respiratory Tract

The human respiratory tract, comprising the upper and lower segments, serves as a critical interface with the external environment. The upper respiratory tract (URT)—including the nostrils, sinuses, pharynx, and oropharynx—is heavily colonized by microbes, while the lower respiratory tract (LRT), composed of the larynx, trachea, bronchi, and lungs, was long thought to be sterile. However, recent molecular studies have revealed that the lungs are not devoid of microbes but act more...
36
Development of the Oral Microbiota01:28

Development of the Oral Microbiota

The establishment of the oral microbiome begins before birth, challenging the long-held belief that the fetal oral cavity is sterile. The presence of oral microbes such as Streptococcus and Fusobacterium in amniotic fluid suggests that microbial exposure may occur in utero, potentially through translocation from the maternal oral or gastrointestinal tract. This early colonization primes the neonatal immune system and sets the stage for subsequent microbial succession. Maternal health,...
37
Nose and Nasal Cavity01:24

Nose and Nasal Cavity

The nose is composed of an observable exterior segment (external nose) and an internal segment within the skull known as the nasal cavity (internal nose). The external nose, visible on the face, consists of a framework of bone and hyaline cartilage enveloped in skin and muscle and lined with a mucous membrane. This structure is supported by the frontal bone, nasal bones, and maxillary bone and is supplemented by a cartilaginous framework comprising the septal nasal cartilage, lateral nasal...
15.8K
Suctioning the Nasopharyngeal Airway01:29

Suctioning the Nasopharyngeal Airway

Nasopharyngeal suctioning is a procedure to remove secretions from the upper part of the respiratory tract that the patient cannot clear independently. It helps maintain airway patency and prevents complications such as aspiration pneumonia.
Equipment Required
5.4K